IGF-1LR3 (0.1mg)

Description

A single-component research material supplied for controlled research environments. IGF-1 LR3 (0.1 mg) is a recombinant analog of Insulin-like Growth Factor 1 featuring an arginine-to-glutamic acid substitution at position 3 and a 13-amino acid N-terminal extension, studied for its potential role in IGF-1 receptor signaling, cell proliferation research, and metabolic pathway exploration in model systems.

Composition

• Insulin-like Growth Factor 1 Long Arg3 (IGF-1 LR3), 83 amino acids
• Appearance: Lyophilized powder in a sealed research vial

Research Focus (non-clinical)

• Protein identity and purity assessment via HPLC/LC-MS and SDS-PAGE
• Studies on IGF-1 receptor binding affinity and downstream Akt/mTOR signal transduction in cell culture models
• Exploration of IGF-1 LR3’s reduced IGFBP binding and extended bioactivity relative to native IGF-1 in laboratory assays
• Stability and reconstitution profiling of IGF-1 LR3 under laboratory storage conditions

For qualified research professionals and institutional laboratories. Not for human use.

Documentation & Quality Assurance

Each lot is sourced through our verified global supply chain with emphasis on traceability and quality control. We work diligently to obtain and maintain third-party analytical reports (HPLC/LC-MS) and Certificates of Analysis for each batch, as part of our ongoing quality process. These documents are reviewed internally and displayed as they become available. Independent third-party testing is also performed on select lots to confirm identity, purity, and alignment with our internal specifications.

Important Notice

This product is intended for laboratory research use only. It is not intended for human or veterinary use, and must not be used for diagnostic, therapeutic, or clinical purposes.
This material is not a drug, medical device, or dietary supplement, and has not been evaluated by the U.S. Food and Drug Administration.

Quality & Manufacturing

All materials are sourced from carefully vetted domestic and international manufacturing partners who follow quality systems consistent with ISO and cGMP principles. Each supplier is reviewed for reliability, documentation integrity, and transparency in testing.

We require a verified purity of 99% or higher and perform independent third-party spot testing to confirm that select lots meet our internal standards for identity, purity, and composition. Where available, endotoxin testing results are included on Certificates of Analysis to verify laboratory purity; their inclusion is for research quality assessment only and does not imply suitability for human or veterinary use.

All research materials are sealed for integrity and packaged for stability during storage and transport from manufacturing through final delivery.